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			 Publication Type 
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			 Key Appraisal Questions 
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			 Primary Evaluation Criteria 
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			 Potential Limitations 
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			 Case Report 
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				- Is the case description comprehensive? 
 
				- Are unique or important aspects highlighted? 
 
				- What is the potential broader significance? 
 
				- Are ethical considerations addressed? 
 
				- How unusual or informative is the case?
 
			 
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				- Detailed description 
 
				- Clinical relevance 
 
				- Potential learning value 
 
				- Ethical considerations
 
			 
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				- Cannot generalize 
 
				- Limited scientific value 
 
				- Potential reporting bias
 
			 
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			 Case Study 
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				- Was the study methodology rigorous? 
 
				- How were data collected and analyzed? 
 
				- What contextual factors were considered? 
 
				- Are findings potentially transferable? 
 
				-  What are the study's limitations?
 
			 
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				- Depth of analysis 
 
				- Contextual understanding 
 
				- Methodological rigor 
 
				-  Potential insights
 
			 
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				- Limited generalizability 
 
				- Potential researcher bias 
 
				- Narrow scope
 
			 
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			 Clinical Practice Guideline 
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				- Was the guideline developed systematically? 
 
				- Are recommendations based on best available evidence? 
 
				- How recently was the guideline updated? 
 
				- Are conflicts of interest disclosed? 
 
				- Does it address multiple clinical scenarios?
 
			 
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				- Evidence quality 
 
				- Comprehensive approach 
 
				- Clarity of recommendations 
 
				- Professional consensus
 
			 
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				- May become outdated 
 
				- Potential funding bias 
 
				- Limited individual patient variation
 
			 
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			 Clinical Protocol 
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				- Are steps clearly defined and sequenced? 
 
				- Is the protocol based on current evidence? 
 
				- Does it provide decision-making guidance? 
 
				- Are potential variations addressed? 
 
				- How flexible is the implementation?
 
			 
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				- Procedural clarity 
 
				- Evidence-based approach 
 
				- Practical applicability 
 
				- Safety considerations
 
			 
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				- May not fit all scenarios 
 
				- Potential oversimplification 
 
				- Limited individual adaptation
 
			 
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			 Consensus/Position Statement 
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				- Who developed the statement? 
 
				- What evidence supports the consensus? 
 
				- How representative are the contributors? 
 
				- Are minority opinions acknowledged? 
 
				- What is the level of agreement?
 
			 
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				- Expert credibility 
 
				- Transparency 
 
				- Breadth of perspective 
 
				- Scientific backing
 
			 
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				- Potential expert bias 
 
				- Limited empirical evidence 
 
				- May reflect opinion over research
 
			 
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			 Financial/Economic Impact Report 
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				- What methodology was used for analysis? 
 
				- Are all relevant costs considered? 
 
				- What are the long-term financial implications? 
 
				- Are assumptions clearly stated? 
 
				- How sensitive are the findings to variations?
 
			 
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				- Comprehensive cost analysis 
 
				- Methodological rigor 
 
				- Transparency of assumptions 
 
				- Long-term perspective
 
			 
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				- Complex modeling 
 
				- Potential predictive limitations 
 
				- Sensitivity to input variables
 
			 
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			 Literature Review 
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				- Was the search strategy comprehensive? 
 
				- How were studies selected and evaluated? 
 
				- Are contradictory findings discussed? 
 
				- Is the review critically analytical? 
 
				- Are gaps in current research identified?
 
			 
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				- Search comprehensiveness 
 
				- Critical analysis 
 
				- Synthesis quality 
 
				- Research gap identification
 
			 
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				- Potential selection bias 
 
				- May not be systematic 
 
				- Dependent on available literature
 
			 
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			 Quality Improvement Report 
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				- What was the specific improvement goal? 
 
				- How was progress measured? 
 
				- What interventions were implemented? 
 
				- Are results statistically significant? 
 
				- Are sustainability and scalability addressed?
 
			 
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				- Measurable outcomes 
 
				- Intervention clarity 
 
				- Statistical validity 
 
				- Potential for broader application
 
			 
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				- May be context-specific 
 
				- Potential implementation challenges 
 
				- Limited long-term data
 
			 
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